A virtual reality social conditioned place preference paradigm for humans: Does trait social anxiety affect approach and avoidance of virtual agents?

Approach and avoidance of positive negative social cues are fundamental to prevent isolation ensure survival. High trait anxiety is characterized by an situations extensive a risk factor for the development disorder (SAD). Therefore, experimental methods assess behavior in humans essential. The conditioned place preference (SCPP) paradigm well-established animal research that used objectively investigate approach–avoidance mechanisms. We retranslated this human using virtual reality. To end, 58 healthy adults were exposed either happy- or angry-looking agent specific room, effects encounter on dwell time as well evaluation room later test without examined. did not observe general SCPP effect ratings but discovered moderation anxiety, which participants with higher spent less angry was present before, suggesting levels foster avoidance. However, further studies needed verify observation substantiate association disorder. discussed strengths, limitations, technical implications our future investigations more comprehensively understand mechanisms involved facilitate new personalized treatment approaches